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Antigenic Specificity | FRAP1 (pT2446) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, DB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FRAP1 belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. FRAP1 is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization. |
Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T2446 of human FRAP1. |
Other Names | MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, Serine/threonine-protein kinase mTOR, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1, MTOR, MTOR, MTOR , MTOR , FRAP, FRAP, FRAP , FRAP , FRAP1, FRAP1, FRAP1 , FRAP1 , FRAP2, FRAP2, FRAP2 , FRAP2 , RAFT1, RAFT1, RAFT1 , RAFT1 , RAPT1, RAPT1, RAPT1 , RAPT1 , Serine/threonine-protein kinase mTOR, Serine/threonine-protein kinase mTOR, Serine/threonine-protein kinase mTOR , Serine/threonine-protein kinase mTOR , FK506-binding protein 12-rapamycin complex-associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1 , FK506-binding protein 12-rapamycin complex-associated protein 1 , FKBP12-rapamycin complex-associated protein, FKBP12-rapamycin complex-associated protein, FK |
Gene, Accession # | NCBI: NP_004949.1, UniProt: P42345 |
Catalog # | abx031982 |
Price | please inquire |
Order / More Info | FRAP1 (pT2446) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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