Nucleophosmin (NPM1) Antibody from ABBEXA LTD
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| Antigenic Specificity | Nucleophosmin (NPM1) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules. In concert with BRCA2, regulates centrosome duplication. Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication. |
| Immunogen | Purified His-tagged NPM1 protein |
| Other Names | B23, NPM, NPM1, Nucleophosmin, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, npm1, nucleophosmin (nucleolar phosphoprotein B23, numatrin), MGC104254, B23, B23, B23 , B23 , NPM, NPM, NPM , NPM , NPM1, NPM1, NPM1 , NPM1 , Nucleophosmin, Nucleophosmin, Nucleophosmin , Nucleophosmin , Nucleolar phosphoprotein B23, Nucleolar phosphoprotein B23, Nucleolar phosphoprotein B23 , Nucleolar phosphoprotein B23 , Nucleolar protein NO38, Nucleolar protein NO38, Nucleolar protein NO38 , Nucleolar protein NO38 , Numatrin, Numatrin, Numatrin , Numatrin , npm1, npm1, npm1 , npm1 , nucleophosmin (nucleolar phosphoprotein B23, nucleophosmin (nucleolar phosphoprotein B23, nucleophosmin (nucleolar phosphoprotein B23 , nucleophosmin (nucleolar phosphoprotein B23 , numatrin), numatrin), numatrin) , numatrin) , MGC104254, MGC104254, MGC104254 , MGC104254 |
| Gene, Accession # | NCBI: NP_001032827.1, NP_002511.1, NP_954654.1, UniProt: P06748 |
| Catalog # | abx034838 |
| Price | please inquire |
| Order / More Info | Nucleophosmin (NPM1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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