Proteasome Activator Subunit 3 (PSME3) Antibody from ABBEXA LTD
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| Antigenic Specificity | Proteasome Activator Subunit 3 (PSME3) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PSME3 antibody is a Rabbit polyclonal antibody against PSME3. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Alternate splicing results in multiple transcript variants. |
| Immunogen | Recombinant protein of human PSME3. |
| Other Names | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki), PSME3, Ki, PA28-gamma, PA28G, REG-GAMMA, proteasome (prosome, proteasome (prosome, proteasome (prosome , proteasome (prosome , macropain) activator subunit 3 (PA28 gamma, macropain) activator subunit 3 (PA28 gamma, macropain) activator subunit 3 (PA28 gamma , macropain) activator subunit 3 (PA28 gamma , Ki), Ki), Ki) , Ki) , PSME3, PSME3, PSME3 , PSME3 , Ki, Ki, Ki , Ki , PA28-gamma, PA28-gamma, PA28-gamma , PA28-gamma , PA28G, PA28G, PA28G , PA28G , REG-GAMMA, REG-GAMMA, REG-GAMMA , REG-GAMMA |
| Gene, Accession # | PSME3, Gene ID: 10197, UniProt: P61289 |
| Catalog # | abx000656 |
| Price | please inquire |
| Order / More Info | Proteasome Activator Subunit 3 (PSME3) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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