Apolipoprotein E (APOE) Antibody from ABBEXA LTD

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Antigenic SpecificityApolipoprotein E (APOE)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpurified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionChylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
ImmunogenKLH-conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human APOE.
Other NamesAD2, Apo-E, APOE, Apolipoprotein E, apolipoprotein E3, LDLCQ5, LPG, MGC1571, apoprotein, Alzheimer disease 2 (APOE*E4-associated, late onset), AD2, AD2, AD2 , AD2 , Apo-E, Apo-E, Apo-E , Apo-E , APOE, APOE, APOE , APOE , Apolipoprotein E, Apolipoprotein E, Apolipoprotein E , Apolipoprotein E , apolipoprotein E3, apolipoprotein E3, apolipoprotein E3 , apolipoprotein E3 , LDLCQ5, LDLCQ5, LDLCQ5 , LDLCQ5 , LPG, LPG, LPG , LPG , MGC1571, MGC1571, MGC1571 , MGC1571 , apoprotein, apoprotein, apoprotein , apoprotein , Alzheimer disease 2 (APOE*E4-associated, late onset), Alzheimer disease 2 (APOE*E4-associated, late onset), Alzheimer disease 2 (APOE*E4-associated, late onset) , Alzheimer disease 2 (APOE*E4-associated, late onset)
Gene, Accession #NCBI: NP_000032.1, UniProt: P02649
Catalog #abx033494
Priceplease inquire
Order / More InfoApolipoprotein E (APOE) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
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https://www.abbexa.com

U.S. Office
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Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413

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Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950


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