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Antigenic Specificity | Apolipoprotein E (APOE) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. |
Immunogen | KLH-conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human APOE. |
Other Names | AD2, Apo-E, APOE, Apolipoprotein E, apolipoprotein E3, LDLCQ5, LPG, MGC1571, apoprotein, Alzheimer disease 2 (APOE*E4-associated, late onset), AD2, AD2, AD2 , AD2 , Apo-E, Apo-E, Apo-E , Apo-E , APOE, APOE, APOE , APOE , Apolipoprotein E, Apolipoprotein E, Apolipoprotein E , Apolipoprotein E , apolipoprotein E3, apolipoprotein E3, apolipoprotein E3 , apolipoprotein E3 , LDLCQ5, LDLCQ5, LDLCQ5 , LDLCQ5 , LPG, LPG, LPG , LPG , MGC1571, MGC1571, MGC1571 , MGC1571 , apoprotein, apoprotein, apoprotein , apoprotein , Alzheimer disease 2 (APOE*E4-associated, late onset), Alzheimer disease 2 (APOE*E4-associated, late onset), Alzheimer disease 2 (APOE*E4-associated, late onset) , Alzheimer disease 2 (APOE*E4-associated, late onset) |
Gene, Accession # | NCBI: NP_000032.1, UniProt: P02649 |
Catalog # | abx033494 |
Price | please inquire |
Order / More Info | Apolipoprotein E (APOE) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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