Phosphorylated Adapter RNA Export Protein (PHAX) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Phosphorylated Adapter RNA Export Protein (PHAX) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Phosphorylated Adapter RNA Export Protein (PHAX) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding complex (CBC) bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly. It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus. Its compartmentalized phosphorylation cycle may also contribute to the directionality of export. Binds strongly to m7G-capped U1 and U5 small nuclear RNAs (snRNAs) in a sequence-unspecific manner and phosphorylation-independent manner (By similarity). Plays also a role in the biogenesis of U3 small nucleolar RNA (snoRNA). Involved in the U3 snoRNA transport from nucleoplasm to Cajal bodies. Binds strongly to m7G-capped U3, U8 and U13 precursor snoRNAs and weakly to trimethylated (TMG) capped U3, U8 and U13 snoRNAs. Binds also to telomerase RNA. |
| Immunogen | KLH-conjugated synthetic peptide between 297-326 amino acids from the C-terminal region of human PHAX. |
| Other Names | PHAX, RNUXA, Phosphorylated adapter RNA export protein, RNA U small nuclear RNA export adapter protein, PHAX, PHAX, PHAX , PHAX , RNUXA, RNUXA, RNUXA , RNUXA , Phosphorylated adapter RNA export protein, Phosphorylated adapter RNA export protein, Phosphorylated adapter RNA export protein , Phosphorylated adapter RNA export protein , RNA U small nuclear RNA export adapter protein, RNA U small nuclear RNA export adapter protein, RNA U small nuclear RNA export adapter protein , RNA U small nuclear RNA export adapter protein |
| Gene, Accession # | PHAX, UniProt: Q9H814 |
| Catalog # | abx027045 |
| Price | please inquire |
| Order / More Info | Phosphorylated Adapter RNA Export Protein (PHAX) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
Orders: orders@abbexa.com
https://www.abbexa.com
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950
Profile of ABBEXA LTD
Return to Antibodies