Mouse Mavs Antibody from ABBEXA LTD

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Antigenic SpecificityMouse Mavs
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionRequired for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
ImmunogenKLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Mavs.
Other NamesMavs, Ips1, Visa, Mitochondrial antiviral-signaling protein, CARD adapter inducing interferon beta, Interferon beta promoter stimulator protein 1, Virus-induced-signaling adapter, Mavs, Mavs, Mavs , Mavs , Ips1, Ips1, Ips1 , Ips1 , Visa, Visa, Visa , Visa , Mitochondrial antiviral-signaling protein, Mitochondrial antiviral-signaling protein, Mitochondrial antiviral-signaling protein , Mitochondrial antiviral-signaling protein , CARD adapter inducing interferon beta, CARD adapter inducing interferon beta, CARD adapter inducing interferon beta , CARD adapter inducing interferon beta , Interferon beta promoter stimulator protein 1, Interferon beta promoter stimulator protein 1, Interferon beta promoter stimulator protein 1 , Interferon beta promoter stimulator protein 1 , Virus-induced-signaling adapter, Virus-induced-signaling adapter, Virus-induced-signaling adapter , Virus-induced-signaling adapter
Gene, Accession #UniProt: Q8VCF0
Catalog #abx031371
Priceplease inquire
Order / More InfoMouse Mavs Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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