R-Spondin 1 (RSPO1) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-R-Spondin 1 (RSPO1) antibody, protein, ELISA kits.
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| Antigenic Specificity | R-Spondin 1 (RSPO1) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | R-Spondin 1, also known as RSPO1, CRISTIN3, FLJ40906. Entrez Protein NP001033722.1. It is a member of the R-spondin family and a 28.9kDa secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.It is activator of the beta catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor signaling pathway that may not use frizzled/LRP receptors. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF beta pathway. Has a essential roles in ovary determination. |
| Immunogen | Purified recombinant fragment of R-spondin1 expressed in E. Coli. |
| Other Names | Roof plate-specific spondin-1, hRspo1, RSPO1, CRISTIN3, FLJ40906, R-Spondin 1, RSPONDIN, Roof plate-specific spondin-1, Roof plate-specific spondin-1, Roof plate-specific spondin-1 , Roof plate-specific spondin-1 , hRspo1, hRspo1, hRspo1 , hRspo1 , RSPO1, RSPO1, RSPO1 , RSPO1 , CRISTIN3, CRISTIN3, CRISTIN3 , CRISTIN3 , FLJ40906, FLJ40906, FLJ40906 , FLJ40906 , R-Spondin 1, R-Spondin 1, R-Spondin 1 , R-Spondin 1 , RSPONDIN, RSPONDIN, RSPONDIN , RSPONDIN |
| Gene, Accession # | RSPO1, Gene ID: 284654, UniProt: Q2MKA7 |
| Catalog # | abx011430 |
| Price | please inquire |
| Order / More Info | R-Spondin 1 (RSPO1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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