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Antigenic Specificity | Unc-51 Like Autophagy Activating Kinase 2 (ULK2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Two human homologs of the yeast autophagy-specific kinase exist: ULK1 (APG1) and ULK2. APG1 plays a critical role in regulating key elements of the autophagy pathway. APG1 stimulates autophagy, leading to autophagy-dependent restriction of cell growth and ultimately cell apoptosis at high levels of activity, and is a negative regulator of mTOR signaling. |
Immunogen | KLH-conjugated synthetic peptide between 235-264 amino acids from the N-terminal region of human ULK2. |
Other Names | ULK2, KIAA0623, Serine/threonine-protein kinase ULK2, Unc-51-like kinase 2, ATG1B, Unc51.2, ULK2, ULK2, ULK2 , ULK2 , KIAA0623, KIAA0623, KIAA0623 , KIAA0623 , Serine/threonine-protein kinase ULK2, Serine/threonine-protein kinase ULK2, Serine/threonine-protein kinase ULK2 , Serine/threonine-protein kinase ULK2 , Unc-51-like kinase 2, Unc-51-like kinase 2, Unc-51-like kinase 2 , Unc-51-like kinase 2 , ATG1B, ATG1B, ATG1B , ATG1B , Unc51.2, Unc51.2, Unc51.2 , Unc51.2 |
Gene, Accession # | UniProt: Q8IYT8 |
Catalog # | abx033875 |
Price | please inquire |
Order / More Info | Unc-51 Like Autophagy Activating Kinase 2 (ULK2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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