Proto-Oncogene Tyrosine-Protein Kinase LCK (LCK) Antibody from ABBEXA LTD

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Antigenic SpecificityProto-Oncogene Tyrosine-Protein Kinase LCK (LCK)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
FormatProtein G purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC, IF/ICC, FCM
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DescriptionLSK, which belongs to the SRC subfamily of Tyr protein kinases, may participate in antigen-induced T-cell activation. It binds to phosphatidylinositol 3'-kinase (PI3K) from T lymphocytes through its SH3 domain and to the tyrosine phosphorylated form of KHDRBS1/p70 through its SH2 domain. LSK is bound to the cytoplasmic domain of either CD4 or CD8. This protein is involved in leukemias by a chromosomal translocation t (1;7) (p34;q34) which involves LCK and T-cell receptor beta chain (TCRB) genes.
ImmunogenKLH-conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human LCK.
Other Nameskinase Lck, LCK, LSK, LSK-T, lymphocyte-specific protein tyrosine kinase, P56-LCK, T cell-specific protein-tyrosine kinase, LCK (Ab-59), Tyrosine-protein kinase Lck, Leukocyte C-terminal Src kinase, Lymphocyte cell-specific protein-tyrosine kinase, Protein YT16, Proto-oncogene Lck, YT16, p56lck, pp58lck, kinase Lck, kinase Lck, kinase Lck , kinase Lck , LCK, LCK, LCK , LCK , LSK, LSK, LSK , LSK , LSK-T, LSK-T, LSK-T , LSK-T , lymphocyte-specific protein tyrosine kinase, lymphocyte-specific protein tyrosine kinase, lymphocyte-specific protein tyrosine kinase , lymphocyte-specific protein tyrosine kinase , P56-LCK, P56-LCK, P56-LCK , P56-LCK , T cell-specific protein-tyrosine kinase, T cell-specific protein-tyrosine kinase, T cell-specific protein-tyrosine kinase , T cell-specific protein-tyrosine kinase , LCK (Ab-59), LCK (Ab-59), LCK (Ab-59) , LCK (Ab-59) , Tyrosine-protein kinase Lck, Tyrosine-protein kinase Lck, Tyrosine-protein kinase Lck , Tyrosine-protein kinase Lck , Leu
Gene, Accession #UniProt: P06239
Catalog #abx033638
Priceplease inquire
Order / More InfoProto-Oncogene Tyrosine-Protein Kinase LCK (LCK) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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