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Antigenic Specificity | Small Ubiquitin Related Modifier Protein 1 (SUMO1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, IF/ICC, FCM, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SUMO1 antibody is a Rabbit polyclonal antibody against SUMO1. Small ubiquitin-related modifier 1, 2 and 3 (SUMO-1, -2 and -3) are members of the ubiquitin-like protein familyThe covalent attachment of the SUMO-1, -2 or -3 (SUMOylation) to target proteins is analogous to ubiquitinationThis post-translational modification is a reversible, multi-step process that is initiated by cleaving a precursor protein to a mature proteinMature SUMO-1, -2 or -3 is then linked to the activating enzyme E1, conjugated to E2 and in conjunction with E3, SUMO-1, -2 or -3 is ligated to the target proteinUbiquitin and the individual SUMO family members are all targeted to different proteins with diverse biological functionsUbiquitin predominantly regulates degradation of its targetIn contrast, SUMO-1 is conjugated to RanGAP, PML, p53 and I?B-? to regulate nuclear trafficking, formation of subnuclear structures, regulation of transcriptional activity and protein stabilitySUMO-2/-3 forms poly-(SUMO) chains, is conjugated to topoisomerase II and APP, regulates chromosomal segregation and cellular responses to environmental stress, and plays a role in the progression of Alzheimer disease. |
Immunogen | A synthetic peptide of human SUMO-1. |
Other Names | DAP1, GAP modifying protein 1, GAP-modifying protein 1, GMP1, OFC10, PIC1, SENP2, Sentrin, Small ubiquitin-related modifier 1, SMT3, SMT3 homolog 3, SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae), SMT3C, SMT3H3, SUMO-1, SUMO1, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1, UBL1, DAP-1, SMALL UBIQUITIN-LIKE MODIFIER 1, suppressor of mif two 3 homolog 1 (yeast), YEAST, HOMOLOG 3, UBIQUITIN-LIKE 1, DAP1, DAP1, DAP1 , DAP1 , GAP modifying protein 1, GAP modifying protein 1, GAP modifying protein 1 , GAP modifying protein 1 , GAP-modifying protein 1, GAP-modifying protein 1, GAP-modifying protein 1 , GAP-modifying protein 1 , GMP1, GMP1, GMP1 , GMP1 , OFC10, OFC10, OFC10 , OFC10 , PIC1, PIC1, PIC1 , PIC1 , SENP2, SENP2, SENP2 , SENP2 , Sentrin, Sentrin, Sentrin , Sentrin , Small ubiquitin-related modifier 1, Small ubiquitin-related modifier 1, Small ubiquitin-related modifier 1 , Small ubiquitin-related modifier 1 , SMT3, |
Gene, Accession # | SUMO1, Gene ID: 7341, UniProt: P63165 |
Catalog # | abx117219 |
Price | please inquire |
Order / More Info | Small Ubiquitin Related Modifier Protein 1 (SUMO1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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