STAM Binding Protein (STAMBP) Antibody from ABBEXA LTD
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| Antigenic Specificity | STAM Binding Protein (STAMBP) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 20 µg, 50 µg, 100 µg, 200 µg+ |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | STAM Binding Protein (STAMBP) antibody is a Rabbit polyclonal antibody against STAMBP. STAMBP is a zinc metalloprotease that specifically cleaves Lys63-linked polyubiquitin chains but does not cleave Lys48-linked polyubiquitin chains. It plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. It potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. It has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. This protein also binds to the SH3 domain of the signal-transducing adaptor molecule required for induction of MYC and cell growth. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization. STAMBP is involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways. |
| Immunogen | Recombinant human STAM-binding protein (1-424AA). |
| Other Names | STAMBP, STAM Binding Protein, Associated Molecule With The SH3 Domain Of STAM, Endosome-Associated Ubiquitin Isopeptidase, AMSH, Testicular Secretory Protein Li 54, STAM-Binding Protein, MICCAP, STAMBP, STAMBP, STAMBP , STAMBP , STAM Binding Protein, STAM Binding Protein, STAM Binding Protein , STAM Binding Protein , Associated Molecule With The SH3 Domain Of STAM, Associated Molecule With The SH3 Domain Of STAM, Associated Molecule With The SH3 Domain Of STAM , Associated Molecule With The SH3 Domain Of STAM , Endosome-Associated Ubiquitin Isopeptidase, Endosome-Associated Ubiquitin Isopeptidase, Endosome-Associated Ubiquitin Isopeptidase , Endosome-Associated Ubiquitin Isopeptidase , AMSH, AMSH, AMSH , AMSH , Testicular Secretory Protein Li 54, Testicular Secretory Protein Li 54, Testicular Secretory Protein Li 54 , Testicular Secretory Protein Li 54 , STAM-Binding Protein, STAM-Binding Protein, STAM-Binding Protein , STAM-Binding Protein , MICCAP, MICCAP, MICCAP , MICCAP |
| Gene, Accession # | STAMBP, Gene ID: 10617, NCBI: NP_006454.1, NM_006463.4, UniProt: O95630 |
| Catalog # | abx110227 |
| Price | please inquire |
| Order / More Info | STAM Binding Protein (STAMBP) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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