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Antigenic Specificity | E3 Ubiquitin-Protein Ligase NEDD4-Like (NEDD4L) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK. |
Immunogen | KLH-conjugated synthetic peptide between 576-604 amino acids from the Central region of human NEDD4L. |
Other Names | NEDD4L, NEDD4 Like E3 Ubiquitin Protein Ligase, KIAA0439, NEDD4-2, RSP5, Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like, E3 Ubiquitin Protein Ligase, HECT-Type E3 Ubiquitin Transferase NED4L, E3 Ubiquitin-Protein Ligase NEDD4-Like, NEDD4.2, Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like, Ubiquitin-Protein Ligase Rsp5, EC 2.3.2.26, EC 2.3.2.36, HNEDD4-2, EC 6.3.2, Nedd4-2, PVNH7, NEDL3, NEDD4L, NEDD4L, NEDD4L , NEDD4L , NEDD4 Like E3 Ubiquitin Protein Ligase, NEDD4 Like E3 Ubiquitin Protein Ligase, NEDD4 Like E3 Ubiquitin Protein Ligase , NEDD4 Like E3 Ubiquitin Protein Ligase , KIAA0439, KIAA0439, KIAA0439 , KIAA0439 , NEDD4-2, NEDD4-2, NEDD4-2 , NEDD4-2 , RSP5, RSP5, RSP5 , RSP5 , Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like, E3 Ubiquitin Protein Ligase, Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like, E3 Ubiquitin Protein Ligase, Neural Precursor Cell Expressed, Developmentally Down |
Gene, Accession # | NEDD4L, Gene ID: 23327, UniProt: Q96PU5 |
Catalog # | abx028438 |
Price | please inquire |
Order / More Info | E3 Ubiquitin-Protein Ligase NEDD4-Like (NEDD4L) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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