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Antigenic Specificity | Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CYP17A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17, 20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in CYP17A1 gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17, 20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. |
Immunogen | KLH-conjugated synthetic peptide between 358-388 amino acids from the Central region of human CYP17A1. |
Other Names | CPT7, CYP17, P450C17, S17AH, CYP17A1, Steroid 17-alpha-hydroxylase/17, 20 lyase, CYPXVII, Cytochrome P450 17A1, Cytochrome P450-C17, Steroid 17-alpha-monooxygenase, cytochrome P450, family 17, subfamily A, polypeptide 1, HGNC:2593, cytochrome P450, family 17, cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia, cytochrome p450 XVIIA1, steroid 17-a, cytochrome P450, family 17, subfamily A, polypeptide 1, CPT7, CPT7, CPT7 , CPT7 , CYP17, CYP17, CYP17 , CYP17 , P450C17, P450C17, P450C17 , P450C17 , S17AH, S17AH, S17AH , S17AH , CYP17A1, CYP17A1, CYP17A1 , CYP17A1 , Steroid 17-alpha-hydroxylase/17, Steroid 17-alpha-hydroxylase/17, Steroid 17-alpha-hydroxylase/17 , Steroid 17-alpha-hydroxylase/17 , 20 lyase, 20 lyase, 20 lyase , 20 lyase , CYPXVII, CYPXVII, CYPXVII , CYPXVII , Cytochrome P450 17A1, Cytochrome P450 17A1, Cytochrome P450 17A1 , Cytochrome P450 17A1 , Cytochrome P450-C17, Cytochrome P450-C17, Cytochrome P450-C17 , Cytochrome P450-C17 , |
Gene, Accession # | NCBI: NP_000093.1, UniProt: P05093 |
Catalog # | abx033739 |
Price | please inquire |
Order / More Info | Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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