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Antigenic Specificity | Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. |
Immunogen | KLH-conjugated synthetic peptide between 10-36 amino acids from the N-terminal region of human AKR1C3. |
Other Names | 17-beta-hydroxysteroid dehydrogenase type 5, 17-beta-HSD 5, 3-alpha-HSD type II, brain, 3-alpha-hydroxysteroid dehydrogenase type 2, 3-alpha-HSD type 2, Chlordecone reductase homolog HAKRb, Dihydrodiol dehydrogenase 3, DD-3, DD3, Dihydrodiol dehydrogenase type I, HA1753, Indanol dehydrogenase, Prostaglandin F synthase, PGFS, Testosterone 17-beta-dehydrogenase 5, Trans-1, 2-dihydrobenzene-1, 2-diol dehydrogenase, AKR1C3, DDH1, HSD17B5, KIAA0119, HAKRB, HAKRe, hluPGFS, aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II), chlordecone reductase homolog, hydroxysteroid (1, Aldo-keto reductase family 1 member C3, Trans-1 2-dihydrobenzene-1 2-diol dehydrogenase, aldo-keto reductase family 1 member C3 (3-alpha hydroxysteroid dehydrogenase, type II), DDX, Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, 17-beta-hydroxysteroid dehydrogenase type 5, 17-beta-hydroxysteroid dehydrogenase type 5, 17-beta-hydroxysteroid dehydrogenase type 5 , 17-beta-hydroxysteroi |
Gene, Accession # | AKR1C3, UniProt: P42330 |
Catalog # | abx025612 |
Price | please inquire |
Order / More Info | Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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