TSC2 (pS1420) Antibody from ABBEXA LTD

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Antigenic SpecificityTSC2 (pS1420)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, IF/ICC, DB
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DescriptionMutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.
ImmunogenKLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1420 of human TSC2.
Other NamesTSC2, LAM, Tuberous sclerosis 2 protein, Tuberous sclerosis 2, TSC4, Tuberin, TSC2, TSC2, TSC2 , TSC2 , LAM, LAM, LAM , LAM , Tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein , Tuberous sclerosis 2 protein , Tuberous sclerosis 2, Tuberous sclerosis 2, Tuberous sclerosis 2 , Tuberous sclerosis 2 , TSC4, TSC4, TSC4 , TSC4 , Tuberin, Tuberin, Tuberin , Tuberin
Gene, Accession #UniProt: P49815
Catalog #abx032002
Priceplease inquire
Order / More InfoTSC2 (pS1420) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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