Docking Protein 4 (DOK4) Antibody from ABBEXA LTD
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| Antigenic Specificity | Docking Protein 4 (DOK4) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | DOK4 antibody is a Rabbit polyclonal antibody against DOK4. The downstream of kinase family (Dok-1-7) are members of a class of docking proteins that interact with receptor tyrosine kinases and, via this interaction, mediate biological responses within the body. Dok-4 (Downstream of kinase-4) is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis. |
| Immunogen | Recombinant protein of human DOK4. |
| Other Names | Docking protein 4, Downstream of tyrosine kinase 4, DOK4, Insulin receptor substrate 5, FLJ10488, IRS5, IRS 5, Docking protein 4, Docking protein 4, Docking protein 4 , Docking protein 4 , Downstream of tyrosine kinase 4, Downstream of tyrosine kinase 4, Downstream of tyrosine kinase 4 , Downstream of tyrosine kinase 4 , DOK4, DOK4, DOK4 , DOK4 , Insulin receptor substrate 5, Insulin receptor substrate 5, Insulin receptor substrate 5 , Insulin receptor substrate 5 , FLJ10488, FLJ10488, FLJ10488 , FLJ10488 , IRS5, IRS5, IRS5 , IRS5 , IRS 5, IRS 5, IRS 5 , IRS 5 |
| Gene, Accession # | DOK4, Gene ID: 55715, UniProt: Q8TEW6 |
| Catalog # | abx000611 |
| Price | please inquire |
| Order / More Info | Docking Protein 4 (DOK4) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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