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Antigenic Specificity | Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. |
Immunogen | KLH-conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human UBE2D1. |
Other Names | UBE2D1, SFT, UBC5A, UBCH5, UBCH5A, Ubiquitin-conjugating enzyme E2 D1, Stimulator of Fe transport, UBC4/5 homolog, Ubiquitin carrier protein D1, Ubiquitin-conjugating enzyme E2 (17) KB 1, Ubiquitin-conjugating enzyme E2-17 kDa 1, Ubiquitin-protein ligase D1, UBC4/5, E2 (17)KB1, Ubiquitin-conjugating enzyme E2(17)KB 1, UBE2D1, UBE2D1, UBE2D1 , UBE2D1 , SFT, SFT, SFT , SFT , UBC5A, UBC5A, UBC5A , UBC5A , UBCH5, UBCH5, UBCH5 , UBCH5 , UBCH5A, UBCH5A, UBCH5A , UBCH5A , Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-conjugating enzyme E2 D1 , Ubiquitin-conjugating enzyme E2 D1 , Stimulator of Fe transport, Stimulator of Fe transport, Stimulator of Fe transport , Stimulator of Fe transport , UBC4/5 homolog, UBC4/5 homolog, UBC4/5 homolog , UBC4/5 homolog , Ubiquitin carrier protein D1, Ubiquitin carrier protein D1, Ubiquitin carrier protein D1 , Ubiquitin carrier protein D1 , Ubiquitin-conjugating enzyme E2 (17) KB 1, Ubiquitin-conjugating enzyme |
Gene, Accession # | UniProt: P51668 |
Catalog # | abx031522 |
Price | please inquire |
Order / More Info | Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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