Myeloid Cell Surface Antigen CD33 (CD33) Antibody from ABBEXA LTD

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Antigenic SpecificityMyeloid Cell Surface Antigen CD33 (CD33)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatascites
Size100 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC, FCM
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DescriptionThe protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells.Preferentially binds to alpha-2,6-linked sialic acid.The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules.Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD).
ImmunogenPurified recombinant fragment of human CD33 (AA: 15-237) expressed in E. coli.
Other NamesCD33, Siglec-3, gp67, p67, p68, p69, p70, p71, p72, p73, SIGLEC3, Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, FLJ00391, CD antigen CD33, CD33, CD33, CD33 , CD33 , Siglec-3, Siglec-3, Siglec-3 , Siglec-3 , gp67, gp67, gp67 , gp67 , p67, p67, p67 , p67 , p68, p68, p68 , p68 , p69, p69, p69 , p69 , p70, p70, p70 , p70 , p71, p71, p71 , p71 , p72, p72, p72 , p72 , p73, p73, p73 , p73 , SIGLEC3, SIGLEC3, SIGLEC3 , SIGLEC3 , Myeloid cell surface antigen CD33, Myeloid cell surface antigen CD33, Myeloid cell surface antigen CD33 , Myeloid cell surface antigen CD33 , Sialic acid-binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3 , Sialic acid-binding Ig-like lectin 3 , FLJ00391, FLJ00391, FLJ00391 , FLJ00391 , CD antigen CD33, CD antigen CD33, CD antigen CD33 , CD antigen CD33
Gene, Accession #CD33, Gene ID: 945, UniProt: P20138
Catalog #abx015798
Priceplease inquire
Order / More InfoMyeloid Cell Surface Antigen CD33 (CD33) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

Customer Service: info@abbexa.com
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Telephone: +44 (0) 1223 755950


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