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Antigenic Specificity | Antigen Peptide Transporter 2 (TAP2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TAP2 antibody is a Rabbit polyclonal antibody against TAP2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Jul 2008]. |
Immunogen | Recombinant protein of human TAP2. |
Other Names | ABCB3, PSF2, RING11, Y1, Antigen peptide transporter 2, APT2, ATP-binding cassette sub-family B member 3, Peptide supply factor 2, Peptide transporter PSF2, PSF-2, Peptide transporter TAP2, Peptide transporter involved in antigen processing 2, Really interesting new gene 11 protein, ABC18, D6S217E, TAP2, ABCB3, ABCB3, ABCB3 , ABCB3 , PSF2, PSF2, PSF2 , PSF2 , RING11, RING11, RING11 , RING11 , Y1, Y1, Y1 , Y1 , Antigen peptide transporter 2, Antigen peptide transporter 2, Antigen peptide transporter 2 , Antigen peptide transporter 2 , APT2, APT2, APT2 , APT2 , ATP-binding cassette sub-family B member 3, ATP-binding cassette sub-family B member 3, ATP-binding cassette sub-family B member 3 , ATP-binding cassette sub-family B member 3 , Peptide supply factor 2, Peptide supply factor 2, Peptide supply factor 2 , Peptide supply factor 2 , Peptide transporter PSF2, Peptide transporter PSF2, Peptide transporter PSF2 , Peptide transporter PSF2 , PSF-2, PSF-2, PSF-2 , PSF-2 , Peptide |
Gene, Accession # | TAP2, Gene ID: 6891, UniProt: Q03519 |
Catalog # | abx001354 |
Price | please inquire |
Order / More Info | Antigen Peptide Transporter 2 (TAP2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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