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Antigenic Specificity | DNA Excision Repair Protein ERCC-1 (ERCC1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ERCC1 Antibody is a Rabbit Polyclonal antibody against ERCC1. The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5? incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. |
Immunogen | Recombinant protein of human ERCC1. |
Other Names | COFS4, DNA excision repair protein ERCC-1, ERCC1, excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence), UV20, excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence), excision repair cross-complementing 1, excision repair protein, RAD10, DNA REPAIR DEFECT UV-20 OF CHINESE HAMSTER OVARY CELLS, COMPLEMENTATION OF EXCISION-REPAIR, COMPLEMENTING DEFECTIVE IN CHINESE HAMSTER, excision repair cross-complementing 1 isoform 1, excision repair cross-complementing 1 isofrom 2, COFS4, COFS4, COFS4, COFS4, DNA excision repair protein ERCC-1, DNA excision repair protein ERCC-1, DNA excision repair protein ERCC-1, DNA excision repair protein ERCC-1, ERCC1, ERCC1, ERCC1, ERCC1, excision repair cross-complementing rodent repair deficiency, excision repair cross-complementing rodent repair deficiency, excision repair cross-complementing rodent repair deficiency, excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence), complementation group 1 (includes overlapping antisense sequence), complementation group 1 (includes overlapping antisense sequence), complementation group 1 (includes overlapping antisense sequence), UV20, UV20, UV20, UV20, excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence), excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence), excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence), excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence), excision repair cross-complementing 1, excision repair cross-complementing 1, excision repair cross-complementing 1, excision repair cross-complementing 1, excision repair protein, excision repair protein, excision repair protein, excision repair protein, RAD10, RAD10, RAD10, RAD10, DNA REPAIR DEFECT UV-20 OF CHINESE HAMSTER OVARY CELLS, DNA REPAIR DEFECT UV-20 OF CHINESE HAMSTER OVARY CELLS, DNA REPAIR DEFECT UV-20 OF CHINESE HAMSTER OVARY CELLS, DNA REPAIR DEFECT UV-20 OF CHINESE HAMSTER OVARY CELLS, COMPLEMENTATION OF EXCISION-REPAIR, COMPLEMENTATION OF EXCISION-REPAIR, COMPLEMENTATION OF EXCISION-REPAIR, COMPLEMENTATION OF EXCISION-REPAIR, COMPLEMENTING DEFECTIVE IN CHINESE HAMSTER, COMPLEMENTING DEFECTIVE IN CHINESE HAMSTER, COMPLEMENTING DEFECTIVE IN CHINESE HAMSTER, COMPLEMENTING DEFECTIVE IN CHINESE HAMSTER, excision repair cross-complementing 1 isoform 1, excision repair cross-complementing 1 isoform 1, excision repair cross-complementing 1 isoform 1, excision repair cross-complementing 1 isoform 1, excision repair cross-complementing 1 isofrom 2, excision repair cross-complementing 1 isofrom 2, excision repair cross-complementing 1 isofrom 2, excision repair cross-complementing 1 isofrom 2 |
Gene, Accession # | ERCC1, Gene ID: 2067, UniProt: P07992 |
Catalog # | abx004041 |
Price | please inquire |
Order / More Info | DNA Excision Repair Protein ERCC-1 (ERCC1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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