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Antigenic Specificity | Netrin Receptor DCC (DCC) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. |
Immunogen | KLH-conjugated synthetic peptide between 643-670 amino acids from the Central region of human DCC. |
Other Names | colorectal cancer suppressor, deleted in colorectal carcinoma, netrin receptor DCC, tumor suppressor protein DCC, DCC, IGDCC1, Immunoglobulin superfamily DCC subclass member 1, colorectal cancer suppressor, colorectal cancer suppressor, colorectal cancer suppressor , colorectal cancer suppressor , deleted in colorectal carcinoma, deleted in colorectal carcinoma, deleted in colorectal carcinoma , deleted in colorectal carcinoma , netrin receptor DCC, netrin receptor DCC, netrin receptor DCC , netrin receptor DCC , tumor suppressor protein DCC, tumor suppressor protein DCC, tumor suppressor protein DCC , tumor suppressor protein DCC , DCC, DCC, DCC , DCC , IGDCC1, IGDCC1, IGDCC1 , IGDCC1 , Immunoglobulin superfamily DCC subclass member 1, Immunoglobulin superfamily DCC subclass member 1, Immunoglobulin superfamily DCC subclass member 1 , Immunoglobulin superfamily DCC subclass member 1 |
Gene, Accession # | DCC, UniProt: P43146 |
Catalog # | abx026737 |
Price | please inquire |
Order / More Info | Netrin Receptor DCC (DCC) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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