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Antigenic Specificity | Alpha Actinin 1 (ACTN1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ACTN1 antibody is a Rabbit polyclonal antibody against ACTN1. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Recombinant protein of human ACTN1. |
Other Names | ACTN1, FLJ40884, FLJ54432, Alpha-actinin-1, Alpha-actinin cytoskeletal isoform, F-actin cross-linking protein, Non-muscle alpha-actinin-1, ACTN1, ACTN1, ACTN1 , ACTN1 , FLJ40884, FLJ40884, FLJ40884 , FLJ40884 , FLJ54432, FLJ54432, FLJ54432 , FLJ54432 , Alpha-actinin-1, Alpha-actinin-1, Alpha-actinin-1 , Alpha-actinin-1 , Alpha-actinin cytoskeletal isoform, Alpha-actinin cytoskeletal isoform, Alpha-actinin cytoskeletal isoform , Alpha-actinin cytoskeletal isoform , F-actin cross-linking protein, F-actin cross-linking protein, F-actin cross-linking protein , F-actin cross-linking protein , Non-muscle alpha-actinin-1, Non-muscle alpha-actinin-1, Non-muscle alpha-actinin-1 , Non-muscle alpha-actinin-1 |
Gene, Accession # | ACTN1, Gene ID: 87, UniProt: P12814 |
Catalog # | abx001074 |
Price | please inquire |
Order / More Info | Alpha Actinin 1 (ACTN1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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