26S Proteasome Regulatory Subunit 4 (PSMC1) Antibody from ABBEXA LTD
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| Antigenic Specificity | 26S Proteasome Regulatory Subunit 4 (PSMC1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µg, |
| Concentration | 1 mg/ml. |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal against the 26S Proteasome Regulatory Subunit 4 (PSMC1) protein. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit and a 20S core alpha subunit interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. This subunit also interacts with the adenovirus E1A protein and this interaction alters the activity of the proteasome. Finally, this subunit interacts with ataxin-7, suggesting a role for the proteasome in the development of spinocerebellar ataxia type 7, a progressive neurodegenerative disorder. |
| Immunogen | Recombinant fragment corresponding to 3-169 AA of human PSMC1. |
| Other Names | PSMC1, Proteasome 26S Subunit, ATPase 1, Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1, 26S Proteasome AAA-ATPase Subunit RPT2, 26S Proteasome Regulatory Subunit 4, 26S Protease Regulatory Subunit 4, Proteasome 26S ATPase Subunit 1, Proteasome 26S Subunit ATPase 1, P26S4, P26s4, P56, S4, PSMC1, PSMC1, PSMC1 , PSMC1 , Proteasome 26S Subunit, ATPase 1, Proteasome 26S Subunit, ATPase 1, Proteasome 26S Subunit, ATPase 1 , Proteasome 26S Subunit, ATPase 1 , Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1, Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1, Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 , Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 , 26S Proteasome AAA-ATPase Subunit RPT2, 26S Proteasome AAA-ATPase Subunit RPT2, 26S Proteasome AAA-ATPase Subunit RPT2 , 26S Proteasome AAA-ATPase Subunit RPT2 , 26S Proteasome Regulatory Subunit 4, 26S Proteasome Regulatory Subunit 4, 26S Proteasome Regulatory Subunit 4 , 26S Proteasome Regulatory Sub |
| Gene, Accession # | PSMC1, Gene ID: 5700, NCBI: NP_001317141.1, NM_001330212.1, NP_002793.2, NM_002802.2, UniProt: P62191 |
| Catalog # | abx122069 |
| Price | please inquire |
| Order / More Info | 26S Proteasome Regulatory Subunit 4 (PSMC1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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