ERBB2 (pY1196) Antibody from ABBEXA LTD
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| Antigenic Specificity | ERBB2 (pY1196) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IF/ICC, DB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1196 of human ERBB2. |
| Other Names | ERBB2, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1, c-erb B2/neu protein, herstatin, metastatic lymph node gene 19 protein, neuroblas, ERBB2, ERBB2, ERBB2 , ERBB2 , v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) , v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) , CD340, CD340, CD340 , CD340 , HER-2, HER-2, HER-2 , HER-2 , HER-2/neu, HER-2/neu, HER-2/neu , HER-2/neu , HER2, HER2, HER2 , HER2 , MLN 19, MLN 19, MLN 19 , MLN 19 , NEU, NEU, NEU , NEU , NGL, NGL, NGL , NGL , TKR1, TKR1, TKR1 , TKR1 , c-erb B2/neu prot |
| Gene, Accession # | NCBI: NP_001005862.1, NP_004439.2, UniProt: P04626 |
| Catalog # | abx032153 |
| Price | please inquire |
| Order / More Info | ERBB2 (pY1196) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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