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Antigenic Specificity | 8-Oxoguanine DNA Glycosylase 1 (OGG1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | OGG1 antibody is a Rabbit polyclonal antibody against OGG1. This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008]. |
Immunogen | Recombinant protein of human OGG1. |
Other Names | HMMH, MUTM, OGH1, HOGG1, OGG1, N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase, AP lyase, MMH, DNA (apurinic or apyrimidinic site) lyase, HMMH, HMMH, HMMH , HMMH , MUTM, MUTM, MUTM , MUTM , OGH1, OGH1, OGH1 , OGH1 , HOGG1, HOGG1, HOGG1 , HOGG1 , OGG1, OGG1, OGG1 , OGG1 , N-glycosylase/DNA lyase, N-glycosylase/DNA lyase, N-glycosylase/DNA lyase , N-glycosylase/DNA lyase , 8-oxoguanine DNA glycosylase, 8-oxoguanine DNA glycosylase, 8-oxoguanine DNA glycosylase , 8-oxoguanine DNA glycosylase , DNA-(apurinic or apyrimidinic site) lyase, DNA-(apurinic or apyrimidinic site) lyase, DNA-(apurinic or apyrimidinic site) lyase , DNA-(apurinic or apyrimidinic site) lyase , AP lyase, AP lyase, AP lyase , AP lyase , MMH, MMH, MMH , MMH , DNA (apurinic or apyrimidinic site) lyase, DNA (apurinic or apyrimidinic site) lyase, DNA (apurinic or apyrimidinic site) lyase , DNA (apurinic or apyrimidinic site) lyase |
Gene, Accession # | OGG1, Gene ID: 4968, UniProt: O15527 |
Catalog # | abx001213 |
Price | please inquire |
Order / More Info | 8-Oxoguanine DNA Glycosylase 1 (OGG1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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