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Antigenic Specificity | Apoptosis Protease Activating Factor 1 (APAF1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APAF1 antibody is a Rabbit polyclonal antibody against APAF1. This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. |
Immunogen | Recombinant protein of human APAF1. |
Other Names | APAF 1, Apaf-1, Apaf1, Apoptotic peptidase activating factor 1, Apoptotic protease activating factor 1, Apoptotic protease activating factor, Apoptotic protease-activating factor 1, CED 4, CED4, KIAA0413, APAF, DKFZp781B1145, APAF 1, APAF 1, APAF 1 , APAF 1 , Apaf-1, Apaf-1, Apaf-1 , Apaf-1 , Apaf1, Apaf1, Apaf1 , Apaf1 , Apoptotic peptidase activating factor 1, Apoptotic peptidase activating factor 1, Apoptotic peptidase activating factor 1 , Apoptotic peptidase activating factor 1 , Apoptotic protease activating factor 1, Apoptotic protease activating factor 1, Apoptotic protease activating factor 1 , Apoptotic protease activating factor 1 , Apoptotic protease activating factor, Apoptotic protease activating factor, Apoptotic protease activating factor , Apoptotic protease activating factor , Apoptotic protease-activating factor 1, Apoptotic protease-activating factor 1, Apoptotic protease-activating factor 1 , Apoptotic protease-activating factor 1 , CED 4, CED 4, CED 4 , CE |
Gene, Accession # | Gene ID: 317, UniProt: O14727 |
Catalog # | abx000846 |
Price | please inquire |
Order / More Info | Apoptosis Protease Activating Factor 1 (APAF1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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