DAXX (pS671) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-DAXX (pS671) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | DAXX (pS671) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, DB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product. This product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product. DAXX is proposed to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6 and TGFBR2. Interaction with HSPB1/HSP27 may prevent interaction with TNFRSF6 and MAP3K5 and block DAXX-mediated apoptosis. In contrast, in lymphoid cells JNC activation and TNFRSF6-mediated apoptosis may not involve DAXX. DAXX seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. This protein down-regulates basal and activated transcription, and it also seems to act as a transcriptional co-repressor and inhibits PAX3 and ETS1 through direct protein-protein interaction. DAXX modulates PAX5 activity. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S671 of human DAXX. |
| Other Names | BING2, DAP6, Death domain-associated protein 6, Daxx, hDaxx, ETS1-associated protein 1, EAP1, Fas death domain-associated protein, ETS1 associated protein 1, Fas DEATH domain- associated protein, BING2, BING2, BING2 , BING2 , DAP6, DAP6, DAP6 , DAP6 , Death domain-associated protein 6, Death domain-associated protein 6, Death domain-associated protein 6 , Death domain-associated protein 6 , Daxx, Daxx, Daxx , Daxx , hDaxx, hDaxx, hDaxx , hDaxx , ETS1-associated protein 1, ETS1-associated protein 1, ETS1-associated protein 1 , ETS1-associated protein 1 , EAP1, EAP1, EAP1 , EAP1 , Fas death domain-associated protein, Fas death domain-associated protein, Fas death domain-associated protein , Fas death domain-associated protein , ETS1 associated protein 1, ETS1 associated protein 1, ETS1 associated protein 1 , ETS1 associated protein 1 , Fas DEATH domain- associated protein, Fas DEATH domain- associated protein, Fas DEATH domain- associated protein , Fas DEATH domain- associated |
| Gene, Accession # | UniProt: Q9UER7 |
| Catalog # | abx032021 |
| Price | please inquire |
| Order / More Info | DAXX (pS671) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
Orders: orders@abbexa.com
https://www.abbexa.com
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950
Profile of ABBEXA LTD
Return to Antibodies