Puma BH3 Domain Antibody from ABBEXA LTD
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|---|---|
| Antigenic Specificity | Puma BH3 Domain |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis. |
| Immunogen | KLH-conjugated synthetic peptide between 119-154 amino acids from human Puma BH3 Domain. |
| Other Names | BBC3, PUMA, Bcl-2-binding component 3, JFY-1, p53 up-regulated modulator of apoptosis, BBC3, BBC3 , BBC3 , BBC3, PUMA, PUMA , PUMA , PUMA, Bcl-2-binding component 3, Bcl-2-binding component 3 , Bcl-2-binding component 3 , Bcl-2-binding component 3, JFY-1, JFY-1 , JFY-1 , JFY-1, p53 up-regulated modulator of apoptosis, p53 up-regulated modulator of apoptosis , p53 up-regulated modulator of apoptosis , p53 up-regulated modulator of apoptosis |
| Gene, Accession # | NCBI: NP_001120712.1, NP_001120713.1, NP_001120714.1, NP_055232.1, UniProt: Q9BXH1 |
| Catalog # | abx027261 |
| Price | please inquire |
| Order / More Info | Puma BH3 Domain Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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