HLA class I histocompatibility antigen, C alpha chain (HLA-C) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-HLA class I histocompatibility antigen, C alpha chain (HLA-C) antibody, protein, ELISA kits.
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| Antigenic Specificity | HLA class I histocompatibility antigen, C alpha chain (HLA-C) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described. |
| Immunogen | KLH-conjugated synthetic peptide between 66-93 amino acids from the Central region of human HLA-C. |
| Other Names | MHCC, Major Histocompatibility Complex Class I C, MHC-C, HLAC, HLA-JY3, HLC-C, HLA-C, PSORS1 Leukocyte Antigen C, HLA class I histocompatibility antigen, Cw-7 alpha chain, MHCC, MHCC, MHCC , MHCC , Major Histocompatibility Complex Class I C, Major Histocompatibility Complex Class I C, Major Histocompatibility Complex Class I C , Major Histocompatibility Complex Class I C , MHC-C, MHC-C, MHC-C , MHC-C , HLAC, HLAC, HLAC , HLAC , HLA-JY3, HLA-JY3, HLA-JY3 , HLA-JY3 , HLC-C, HLC-C, HLC-C , HLC-C , HLA-C, HLA-C, HLA-C , HLA-C , PSORS1 Leukocyte Antigen C, PSORS1 Leukocyte Antigen C, PSORS1 Leukocyte Antigen C , PSORS1 Leukocyte Antigen C , HLA class I histocompatibility antigen, Cw-7 alpha chain, HLA class I histocompatibility antigen, Cw-7 alpha chain, HLA class I histocompatibility antigen, Cw-7 alpha chain , HLA class I histocompatibility antigen, Cw-7 alpha chain |
| Gene, Accession # | UniProt: P10321 |
| Catalog # | abx029839 |
| Price | please inquire |
| Order / More Info | HLA class I histocompatibility antigen, C alpha chain (HLA-C) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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