Tuberous Sclerosis Protein 2 (TSC2) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Tuberous Sclerosis Protein 2 (TSC2) antibody, protein, ELISA kits.
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| Antigenic Specificity | Tuberous Sclerosis Protein 2 (TSC2) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. Stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro. Mutations in TSC2 lead to constitutive activation of RAP1A in tumors. |
| Immunogen | KLH-conjugated synthetic peptide between 1364-1393 amino acids from the Central region of human TSC2. |
| Other Names | TSC2, LAM, Tuberous sclerosis 2 protein, Tuberous sclerosis 2, TSC4, Tuberin, TSC2, TSC2, TSC2 , TSC2 , LAM, LAM, LAM , LAM , Tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein , Tuberous sclerosis 2 protein , Tuberous sclerosis 2, Tuberous sclerosis 2, Tuberous sclerosis 2 , Tuberous sclerosis 2 , TSC4, TSC4, TSC4 , TSC4 , Tuberin, Tuberin, Tuberin , Tuberin |
| Gene, Accession # | UniProt: P49815 |
| Catalog # | abx034676 |
| Price | please inquire |
| Order / More Info | Tuberous Sclerosis Protein 2 (TSC2) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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