Edit |   |
---|---|
Antigenic Specificity | HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HLA-DRA antibody is a Rabbit polyclonal antibody against HLA-DRA. HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008]. |
Immunogen | Recombinant protein of human HLA-DRA. |
Other Names | HLA-DRA, HLA-DRA1, HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen DRA, MLRW, HLA-DRA, HLA-DRA, HLA-DRA , HLA-DRA , HLA-DRA1, HLA-DRA1, HLA-DRA1 , HLA-DRA1 , HLA class II histocompatibility antigen, HLA class II histocompatibility antigen, HLA class II histocompatibility antigen , HLA class II histocompatibility antigen , DR alpha chain, DR alpha chain, DR alpha chain , DR alpha chain , MHC class II antigen DRA, MHC class II antigen DRA, MHC class II antigen DRA , MHC class II antigen DRA , MLRW, MLRW, MLRW , MLRW |
Gene, Accession # | HLA-DRA, Gene ID: 3122, UniProt: P01903 |
Catalog # | abx001330 |
Price | please inquire |
Order / More Info | HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950