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Antigenic Specificity | Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CYR61 antibody is a Rabbit polyclonal antibody against CYR61. Cyr61 is a secreted heparin binding protein, encoded by a growth factor-inducible immediate-early gene, that associates with the extracellular matrix and connective tissue. Cyr61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse Cyr61 homolog, Fisp12. As an angiogenic inducer, Cyr61 binds to the cell surface receptor Integrin aV/b3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Expression of Cyr61 is elevated during vessel growth, wound healing and chondrocyte differentiation. Cyr61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression. |
Immunogen | Recombinant protein of human CYR61. |
Other Names | CYR61, IGFBP10, IGF binding protein 10, IBP 10, CCN family member 1, CCN1, Protein CYR61, Cysteine-rich angiogenic inducer 61, Insulin-like growth factor-binding protein 10, IBP-10, IGF-binding protein 10, IGFBP-10, Protein GIG1, GIG1, CYR61, CYR61, CYR61 , CYR61 , IGFBP10, IGFBP10, IGFBP10 , IGFBP10 , IGF binding protein 10, IGF binding protein 10, IGF binding protein 10 , IGF binding protein 10 , IBP 10, IBP 10, IBP 10 , IBP 10 , CCN family member 1, CCN family member 1, CCN family member 1 , CCN family member 1 , CCN1, CCN1, CCN1 , CCN1 , Protein CYR61, Protein CYR61, Protein CYR61 , Protein CYR61 , Cysteine-rich angiogenic inducer 61, Cysteine-rich angiogenic inducer 61, Cysteine-rich angiogenic inducer 61 , Cysteine-rich angiogenic inducer 61 , Insulin-like growth factor-binding protein 10, Insulin-like growth factor-binding protein 10, Insulin-like growth factor-binding protein 10 , Insulin-like growth factor-binding protein 10 , IBP-10, IBP-10, IBP-10 , IBP-10 , IGF-bi |
Gene, Accession # | CCN1, Gene ID: 3491, UniProt: O00622 |
Catalog # | abx001028 |
Price | please inquire |
Order / More Info | Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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