Nuclear Receptor Subfamily 2 Group F Member 6 (NR2F6) Antibody from ABBEXA LTD
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| Antigenic Specificity | Nuclear Receptor Subfamily 2 Group F Member 6 (NR2F6) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4 (+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock; is required early in the development of the locus coeruleus (LC). |
| Immunogen | KLH-conjugated synthetic peptide between 25-53 amino acids from the N-terminal region of human NR2F6. |
| Other Names | EAR2, ERBAL2, NR2F6, Orphan nuclear receptor EAR-2, V-erbA related protein EAR-2, Nuclear receptor subfamily 2 group F member 6, V-erbA-related protein 2, nuclear receptor subfamily 2, group F, member 6, EAR-2, ERBA-related gene-2, v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2, EAR2, EAR2, EAR2 , EAR2 , ERBAL2, ERBAL2, ERBAL2 , ERBAL2 , NR2F6, NR2F6, NR2F6 , NR2F6 , Orphan nuclear receptor EAR-2, Orphan nuclear receptor EAR-2, Orphan nuclear receptor EAR-2 , Orphan nuclear receptor EAR-2 , V-erbA related protein EAR-2, V-erbA related protein EAR-2, V-erbA related protein EAR-2 , V-erbA related protein EAR-2 , Nuclear receptor subfamily 2 group F member 6, Nuclear receptor subfamily 2 group F member 6, Nuclear receptor subfamily 2 group F member 6 , Nuclear receptor subfamily 2 group F member 6 , V-erbA-related protein 2, V-erbA-related protein 2, V-erbA-related protein 2 , V-erbA-related protein 2 , nuclear receptor subfamily 2, group F, member 6, nuclear |
| Gene, Accession # | NR2F6, UniProt: P10588 |
| Catalog # | abx029116 |
| Price | please inquire |
| Order / More Info | Nuclear Receptor Subfamily 2 Group F Member 6 (NR2F6) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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