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Antigenic Specificity | Myc Box-Dependent-Interacting Protein 1 (BIN1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. |
Immunogen | KLH-conjugated synthetic peptide between 360-389 amino acids from the Central region of human BIN1. |
Other Names | AMPH2, AMPHL, SH3P9, Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, BIN1, Myc box-dependent-interacting protein 1, DKFZp547F068, MGC10367, amphiphysin-like, box dependant MYC interacting protein 1, AMPH2, AMPH2, AMPH2 , AMPH2 , AMPHL, AMPHL, AMPHL , AMPHL , SH3P9, SH3P9, SH3P9 , SH3P9 , Amphiphysin II, Amphiphysin II, Amphiphysin II , Amphiphysin II , Amphiphysin-like protein, Amphiphysin-like protein, Amphiphysin-like protein , Amphiphysin-like protein , Box-dependent myc-interacting protein 1, Box-dependent myc-interacting protein 1, Box-dependent myc-interacting protein 1 , Box-dependent myc-interacting protein 1 , Bridging integrator 1, Bridging integrator 1, Bridging integrator 1 , Bridging integrator 1 , BIN1, BIN1, BIN1 , BIN1 , Myc box-dependent-interacting protein 1, Myc box-dependent-interacting protein 1, Myc box-dependent-interacting protein 1 , Myc box-dependent-interacting protein 1 , DKFZp547F068, DKFZp |
Gene, Accession # | BIN1, UniProt: O00499 |
Catalog # | abx027986 |
Price | please inquire |
Order / More Info | Myc Box-Dependent-Interacting Protein 1 (BIN1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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