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Antigenic Specificity | Polycomb Complex Protein BMI-1 (BMI1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BMI is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin ligase activity of RNF2/RING2. BMI cooperates with the MYC oncogene to produce B-lymphomas. |
Immunogen | KLH-conjugated synthetic peptide between 257-286 amino acids from the C-terminal region of human BMI1. |
Other Names | Bmi1, BMI1 polycomb ring finger oncogene, FLVI2/BMI1, PCGF4, RNF51, B lymphoma Mo-MLV insertion region 1 homolog, flvi-2/bmi-1, murine leukemia viral (bmi-1) oncogene homolog, polycomb complex protein BMI-1, polycomb group RING finger protein 4, polycomb, Bmi-1, RING finger protein 51, Polycomb complex protein BMI 1, MGC12685, Bmi1, Bmi1, Bmi1 , Bmi1 , BMI1 polycomb ring finger oncogene, BMI1 polycomb ring finger oncogene, BMI1 polycomb ring finger oncogene , BMI1 polycomb ring finger oncogene , FLVI2/BMI1, FLVI2/BMI1, FLVI2/BMI1 , FLVI2/BMI1 , PCGF4, PCGF4, PCGF4 , PCGF4 , RNF51, RNF51, RNF51 , RNF51 , B lymphoma Mo-MLV insertion region 1 homolog, B lymphoma Mo-MLV insertion region 1 homolog, B lymphoma Mo-MLV insertion region 1 homolog , B lymphoma Mo-MLV insertion region 1 homolog , flvi-2/bmi-1, flvi-2/bmi-1, flvi-2/bmi-1 , flvi-2/bmi-1 , murine leukemia viral (bmi-1) oncogene homolog, murine leukemia viral (bmi-1) oncogene homolog, murine leukemia viral (bmi-1) oncogene ho |
Gene, Accession # | NCBI: NP_001190991.1, NP_005171.4, UniProt: P35226 |
Catalog # | abx031610 |
Price | please inquire |
Order / More Info | Polycomb Complex Protein BMI-1 (BMI1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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