Ubiquitin Specific Peptidase 8 (USP8) Antibody from ABBEXA LTD
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| Antigenic Specificity | Ubiquitin Specific Peptidase 8 (USP8) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. This antibody is supplied as crude ascites. |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the C-terminal region of human USP8. |
| Other Names | USP8, KIAA0055, UBPY, Ubiquitin carboxyl-terminal hydrolase 8, Deubiquitinating enzyme 8, Ubiquitin isopeptidase Y, Ubiquitin thioesterase 8, Ubiquitin-specific-processing protease 8, HumORF8, USP8, USP8, USP8 , USP8 , KIAA0055, KIAA0055, KIAA0055 , KIAA0055 , UBPY, UBPY, UBPY , UBPY , Ubiquitin carboxyl-terminal hydrolase 8, Ubiquitin carboxyl-terminal hydrolase 8, Ubiquitin carboxyl-terminal hydrolase 8 , Ubiquitin carboxyl-terminal hydrolase 8 , Deubiquitinating enzyme 8, Deubiquitinating enzyme 8, Deubiquitinating enzyme 8 , Deubiquitinating enzyme 8 , Ubiquitin isopeptidase Y, Ubiquitin isopeptidase Y, Ubiquitin isopeptidase Y , Ubiquitin isopeptidase Y , Ubiquitin thioesterase 8, Ubiquitin thioesterase 8, Ubiquitin thioesterase 8 , Ubiquitin thioesterase 8 , Ubiquitin-specific-processing protease 8, Ubiquitin-specific-processing protease 8, Ubiquitin-specific-processing protease 8 , Ubiquitin-specific-processing protease 8 , HumORF8, HumORF8, HumORF8 , HumORF8 |
| Gene, Accession # | UniProt: P40818 |
| Catalog # | abx025424 |
| Price | please inquire |
| Order / More Info | Ubiquitin Specific Peptidase 8 (USP8) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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