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Antigenic Specificity | MEK Kinase Kinase 3 (MAP4K3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MAP4K3 encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3). |
Immunogen | Recombinant protein encoding human MAP4K3. |
Other Names | Germinal center kinase related protein kinase, GLK, kinase KHS2, M4K3, MAP4K3, MAPK/ERK kinase kinase kinase 3, MEK kinase kinase 3, MEKKK 3, MEKKK3, MAPKKKK3, RAB8IPL1, Mitogen-activated protein kinase kinase kinase kinase 3, Germinal center kinase-related protein kinase, Germinal center kinase related protein kinase, Germinal center kinase related protein kinase, Germinal center kinase related protein kinase , Germinal center kinase related protein kinase , GLK, GLK, GLK , GLK , kinase KHS2, kinase KHS2, kinase KHS2 , kinase KHS2 , M4K3, M4K3, M4K3 , M4K3 , MAP4K3, MAP4K3, MAP4K3 , MAP4K3 , MAPK/ERK kinase kinase kinase 3, MAPK/ERK kinase kinase kinase 3, MAPK/ERK kinase kinase kinase 3 , MAPK/ERK kinase kinase kinase 3 , MEK kinase kinase 3, MEK kinase kinase 3, MEK kinase kinase 3 , MEK kinase kinase 3 , MEKKK 3, MEKKK 3, MEKKK 3 , MEKKK 3 , MEKKK3, MEKKK3, MEKKK3 , MEKKK3 , MAPKKKK3, MAPKKKK3, MAPKKKK3 , MAPKKKK3 , RAB8IPL1, RAB8IPL1, RAB8IPL1 , RAB8IPL1 , Mitogen-activ |
Gene, Accession # | MAP4K3, NCBI: NP_001257354.1, NP_003609.2, UniProt: Q8IVH8 |
Catalog # | abx034546 |
Price | please inquire |
Order / More Info | MEK Kinase Kinase 3 (MAP4K3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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