ABL1 (pY134) Antibody from ABBEXA LTD
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| Antigenic Specificity | ABL1 (pY134) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, IHC, DB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ABL1 is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t (9;22) translocation results in the head-to-tail fusion of the BCR and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y134 of human ABL1. |
| Other Names | ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl, ABL proto-oncogene 1 non-receptor tyrosine kinase, v-abl Abelson murine leukemia viral oncogene homolog 1, c-abl oncogene 1 receptor tyrosine kinase, c-abl oncogene 1 non-receptor tyrosine kinase, bcr/c-abl oncogene protein, proto-oncogene c-Abl, proto-oncogene tyrosine-protein kinase ABL1, tyrosine-protein kinase ABL1, Abelson tyrosine-protein kinase 1, c-ABL1, Abelson murine leukemia viral oncogene homolog 1, ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl, ABL proto-oncogene 1 non-receptor tyrosine kinase, v-abl Abelson murine leukemia viral oncogene homolog 1, c-abl oncogene 1 receptor tyrosine kinase, c-abl oncogene 1 non-receptor tyrosine kinase, bcr/c-abl oncogene protein, proto-oncogene c-Abl, proto-oncogene tyrosine-protein kinase ABL1, tyrosine-protein kinase ABL1, Abelson tyrosine-protein kinase 1, c-ABL1, Abelson murine leukemia viral oncogene homolog 1, ABL proto-oncogene 1, non-receptor tyrosine kinase, c-abl oncogene 1, receptor |
| Gene, Accession # | ABL1, Gene ID: 25, UniProt: P00519 |
| Catalog # | abx031820 |
| Price | please inquire |
| Order / More Info | ABL1 (pY134) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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