Protein Tyrosine Phosphatase, Non Receptor Type 5 (PTPN5) Antibody from ABBEXA LTD
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| Antigenic Specificity | Protein Tyrosine Phosphatase, Non Receptor Type 5 (PTPN5) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | STEP (Protein-tyrosine phosphatase striatum-enriched) is a neural-specific protein-tyrosine phosphatase. It is also known as PTPN5 (tyrosine-protein phosphatase, non-receptor type 5). STEP immunoreactive areas are most intense in the regions of the CNS receiving a dopaminergic input (e.g. striatum, basal ganglia). STEP is part of the NMDA receptor (R) complex and inhibits NMDAR single-channel activity and NMDAR-mediated synaptic current. Phosphorylation of STEP, via D1 and PKA activation by dopamine, decreases the activity of STEP by reducing its affinity for substrate. |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PTPN5. |
| Other Names | Neural-Specific Protein-Tyrosine Phosphatase, Striatum-Enriched Protein-Tyrosine Phosphatase, Step, Ptpn5, protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched), FLJ14427, PTPSTEP, Tyrosine-protein phosphatase non-receptor type 5, Neural-Specific Protein-Tyrosine Phosphatase, Neural-Specific Protein-Tyrosine Phosphatase, Neural-Specific Protein-Tyrosine Phosphatase , Neural-Specific Protein-Tyrosine Phosphatase , Striatum-Enriched Protein-Tyrosine Phosphatase, Striatum-Enriched Protein-Tyrosine Phosphatase, Striatum-Enriched Protein-Tyrosine Phosphatase , Striatum-Enriched Protein-Tyrosine Phosphatase , Step, Step, Step , Step , Ptpn5, Ptpn5, Ptpn5 , Ptpn5 , protein tyrosine phosphatase, protein tyrosine phosphatase, protein tyrosine phosphatase , protein tyrosine phosphatase , non-receptor type 5 (striatum-enriched), non-receptor type 5 (striatum-enriched), non-receptor type 5 (striatum-enriched) , non-receptor type 5 (striatum-enriched) , FLJ14427, FLJ14427, FL |
| Gene, Accession # | UniProt: P54829 |
| Catalog # | abx029236 |
| Price | please inquire |
| Order / More Info | Protein Tyrosine Phosphatase, Non Receptor Type 5 (PTPN5) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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