Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Antibody from ABBEXA LTD

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Antigenic SpecificityReceptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatascites
Size100 µl,
Concentrationn/a
ApplicationsELISA, WB, IF/ICC
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DescriptionROR1, a type I membrane protein, is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. The ROR-family receptor tyrosine kinases consist of two structurally related proteins, ROR1 and ROR2. These proteins are characterized by having intracellular tyrosine kinase domains, which are highly related to Trk-family kinases, extracellular Frizzled-like cysteine-rich domains (CRDs) and Kringle domains. The ROR family members are highly conserved among species, such as C. elegans, Drosophila, Xenopus and mammals. ROR1 and ROR2 are both involved in organogenesis with particular emphasis in neuronal differentiation. Increased expression of ROR1 in acute lymphoblastic leukemias (ALLs) as well as chronic lymphocytic leukemias (CLLs) implicate this protein as a potential tool for targeted immunotherapy in these diseases.
ImmunogenRecombinant extracellular fragment of human ROR1 (aa30-406) fused with hIgGFc tag, expressed in HEK293 cells.
Other NamesNeurotrophic Tyrosine Kinase, Receptor-Related 1 Ror1 Ntrkr1, NTRKR1, dJ537F10.1, ROR1, Tyrosine-protein kinase transmembrane receptor ROR1, receptor-related 1, receptor tyrosine kinase-like orphan receptor 1, MGC99659, neurotrophic tyrosine kinase receptor-related 1, Neurotrophic Tyrosine Kinase, Neurotrophic Tyrosine Kinase, Neurotrophic Tyrosine Kinase , Neurotrophic Tyrosine Kinase , Receptor-Related 1 Ror1 Ntrkr1, Receptor-Related 1 Ror1 Ntrkr1, Receptor-Related 1 Ror1 Ntrkr1 , Receptor-Related 1 Ror1 Ntrkr1 , NTRKR1, NTRKR1, NTRKR1 , NTRKR1 , dJ537F10.1, dJ537F10.1, dJ537F10.1 , dJ537F10.1 , ROR1, ROR1, ROR1 , ROR1 , Tyrosine-protein kinase transmembrane receptor ROR1, Tyrosine-protein kinase transmembrane receptor ROR1, Tyrosine-protein kinase transmembrane receptor ROR1 , Tyrosine-protein kinase transmembrane receptor ROR1 , receptor-related 1, receptor-related 1, receptor-related 1 , receptor-related 1 , receptor tyrosine kinase-like orphan receptor 1, receptor tyrosin
Gene, Accession #ROR1, Gene ID: 4919, UniProt: Q01973
Catalog #abx011486
Priceplease inquire
Order / More InfoReceptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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