Amphiregulin (AREG) Antibody from ABBEXA LTD

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Antigenic SpecificityAmphiregulin (AREG)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatimmunogen affinity purified
Size100 µg,
Concentration2 mg/ml
ApplicationsELISA, WB, IHC
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DescriptionAmphiregulin (AREG) antibody is a Rabbit polyclonal antibody for the detection of Amphiregulin.

Amphiregulin (AREG) is one of the ligands of the epidermal growth factor receptor (EGFR). AREG plays a central role in mammary gland development and branching morphogenesis in organs and is expressed both in physiological and in cancerous tissues. The AREG protein is synthesized as a 252-amino acid transmembrane precursor, pro-AREG. At the plasma membrane, pro-AREG is subjected to sequential proteolytic cleavages within its ectodomain and is then released as the soluble AREG protein. Depending on the cell type and microenvironment, AREG can be produced in multiple cellular and mature forms using alternative pro-AREG cleavage sites and glycosylation motifs. Post-translastional modfications of 50-kDa pro-AREG produces a major soluble 43-kDa form, 28-, 26-, 16-kDa membrane anchored forms, and soluble 21-, 19-, and 9-kDa forms (PMID: 9642297).
Immunogenamphiregulin
Other NamesAREG, Amphiregulin, AR, CRDGF, SDGF, Colorectum Cell-Derived Growth Factor, Schwannoma-Derived Growth Factor, AREG, AREG, AREG , AREG , Amphiregulin, Amphiregulin, Amphiregulin , Amphiregulin , AR, AR, AR , AR , CRDGF, CRDGF, CRDGF , CRDGF , SDGF, SDGF, SDGF , SDGF , Colorectum Cell-Derived Growth Factor, Colorectum Cell-Derived Growth Factor, Colorectum Cell-Derived Growth Factor , Colorectum Cell-Derived Growth Factor , Schwannoma-Derived Growth Factor, Schwannoma-Derived Growth Factor, Schwannoma-Derived Growth Factor , Schwannoma-Derived Growth Factor
Gene, Accession #AREG, Gene ID: 374, UniProt: P15514
Catalog #abx148289
Priceplease inquire
Order / More InfoAmphiregulin (AREG) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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P: +44 (0) 1223 755950

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