Edit |   |
---|---|
Antigenic Specificity | Amphiregulin (AREG) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Amphiregulin (AREG) antibody is a Rabbit polyclonal antibody for the detection of Amphiregulin. Amphiregulin (AREG) is one of the ligands of the epidermal growth factor receptor (EGFR). AREG plays a central role in mammary gland development and branching morphogenesis in organs and is expressed both in physiological and in cancerous tissues. The AREG protein is synthesized as a 252-amino acid transmembrane precursor, pro-AREG. At the plasma membrane, pro-AREG is subjected to sequential proteolytic cleavages within its ectodomain and is then released as the soluble AREG protein. Depending on the cell type and microenvironment, AREG can be produced in multiple cellular and mature forms using alternative pro-AREG cleavage sites and glycosylation motifs. Post-translastional modfications of 50-kDa pro-AREG produces a major soluble 43-kDa form, 28-, 26-, 16-kDa membrane anchored forms, and soluble 21-, 19-, and 9-kDa forms (PMID: 9642297). |
Immunogen | amphiregulin |
Other Names | AREG, Amphiregulin, AR, CRDGF, SDGF, Colorectum Cell-Derived Growth Factor, Schwannoma-Derived Growth Factor, AREG, AREG, AREG , AREG , Amphiregulin, Amphiregulin, Amphiregulin , Amphiregulin , AR, AR, AR , AR , CRDGF, CRDGF, CRDGF , CRDGF , SDGF, SDGF, SDGF , SDGF , Colorectum Cell-Derived Growth Factor, Colorectum Cell-Derived Growth Factor, Colorectum Cell-Derived Growth Factor , Colorectum Cell-Derived Growth Factor , Schwannoma-Derived Growth Factor, Schwannoma-Derived Growth Factor, Schwannoma-Derived Growth Factor , Schwannoma-Derived Growth Factor |
Gene, Accession # | AREG, Gene ID: 374, UniProt: P15514 |
Catalog # | abx148289 |
Price | please inquire |
Order / More Info | Amphiregulin (AREG) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950