Edit |   |
---|---|
Antigenic Specificity | PDX1 (p11) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, IF/ICC, DB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this protein are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). |
Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T11 of human PDX1. |
Other Names | GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1, PDHX, PDX1, Pyruvate dehydrogenase protein X component, mitochondrial, Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex, E3-binding protein, Lipoyl-containing pyruvate dehydrogenase complex component X, proX, Pancreas/duodenum homeobox protein 1, Glucose-sensitive factor, Insulin promoter factor 1, Insulin upstream factor 1, Islet/duodenum homeobox-1, Somatostatin-transactivating factor 1, GSF, GSF, GSF , GSF , IPF1, IPF1, IPF1 , IPF1 , IUF1, IUF1, IUF1 , IUF1 , IDX-1, IDX-1, IDX-1 , IDX-1 , MODY4, MODY4, MODY4 , MODY4 , PDX-1, PDX-1, PDX-1 , PDX-1 , STF-1, STF-1, STF-1 , STF-1 , PDHX, PDHX, PDHX , PDHX , PDX1, PDX1, PDX1 , PDX1 , Pyruvate dehydrogenase protein X component, Pyruvate dehydrogenase protein X component, Pyruvate dehydrogenase protein X component , Pyruvate dehydrogenase protein X component , mitochondrial, mitochondrial, mitochondrial , mitochondrial , Dihydrolipoamide dehydrogenase-bi |
Gene, Accession # | UniProt: P52945 |
Catalog # | abx032067 |
Price | please inquire |
Order / More Info | PDX1 (p11) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950