Sirtuin 2 (SIRT2) Antibody from ABBEXA LTD

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Antigenic SpecificitySirtuin 2 (SIRT2)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size100 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionSIRT2 antibody is a Rabbit polyclonal antibody against SIRT2. Sirtuins are members of the NAD-dependent histone deacetylase family of proteins that participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and agingSIRT2, a human homolog of the yeast SIR2 (silent information regulator-2), functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clustersSIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycleSIRT2 is part of a phosphorylation cascade where it is phosphorylated late in G(2), during M, and into the period of cytokinesisInhibition of SIRT2 is reported to rescue alpha-synuclein toxicity and modify inclusion morphology in a cellular model of Parkinsons disease.
ImmunogenC term -peptide of human SIRT2.
Other NamesNAD-dependent deacetylase sirtuin-2, SIR2-like 2, NAD-dependent protein deacetylase sirtuin-2, Regulatory protein SIR2 homolog 2, SIR2-like protein 2, SIRT2, SIR2L, SIR2L2, SIR2, NAD-dependent deacetylase sirtuin-2, NAD-dependent deacetylase sirtuin-2, NAD-dependent deacetylase sirtuin-2 , NAD-dependent deacetylase sirtuin-2 , SIR2-like 2, SIR2-like 2, SIR2-like 2 , SIR2-like 2 , NAD-dependent protein deacetylase sirtuin-2, NAD-dependent protein deacetylase sirtuin-2, NAD-dependent protein deacetylase sirtuin-2 , NAD-dependent protein deacetylase sirtuin-2 , Regulatory protein SIR2 homolog 2, Regulatory protein SIR2 homolog 2, Regulatory protein SIR2 homolog 2 , Regulatory protein SIR2 homolog 2 , SIR2-like protein 2, SIR2-like protein 2, SIR2-like protein 2 , SIR2-like protein 2 , SIRT2, SIRT2, SIRT2 , SIRT2 , SIR2L, SIR2L, SIR2L , SIR2L , SIR2L2, SIR2L2, SIR2L2 , SIR2L2 , SIR2, SIR2, SIR2 , SIR2
Gene, Accession #SIRT2, Gene ID: 22933, UniProt: Q8IXJ6
Catalog #abx117000
Priceplease inquire
Order / More InfoSirtuin 2 (SIRT2) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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