Edit |   |
---|---|
Antigenic Specificity | Sirtuin 2 (SIRT2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SIRT2 antibody is a Rabbit polyclonal antibody against SIRT2. Sirtuins are members of the NAD-dependent histone deacetylase family of proteins that participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and agingSIRT2, a human homolog of the yeast SIR2 (silent information regulator-2), functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clustersSIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycleSIRT2 is part of a phosphorylation cascade where it is phosphorylated late in G(2), during M, and into the period of cytokinesisInhibition of SIRT2 is reported to rescue alpha-synuclein toxicity and modify inclusion morphology in a cellular model of Parkinsons disease. |
Immunogen | C term -peptide of human SIRT2. |
Other Names | NAD-dependent deacetylase sirtuin-2, SIR2-like 2, NAD-dependent protein deacetylase sirtuin-2, Regulatory protein SIR2 homolog 2, SIR2-like protein 2, SIRT2, SIR2L, SIR2L2, SIR2, NAD-dependent deacetylase sirtuin-2, NAD-dependent deacetylase sirtuin-2, NAD-dependent deacetylase sirtuin-2 , NAD-dependent deacetylase sirtuin-2 , SIR2-like 2, SIR2-like 2, SIR2-like 2 , SIR2-like 2 , NAD-dependent protein deacetylase sirtuin-2, NAD-dependent protein deacetylase sirtuin-2, NAD-dependent protein deacetylase sirtuin-2 , NAD-dependent protein deacetylase sirtuin-2 , Regulatory protein SIR2 homolog 2, Regulatory protein SIR2 homolog 2, Regulatory protein SIR2 homolog 2 , Regulatory protein SIR2 homolog 2 , SIR2-like protein 2, SIR2-like protein 2, SIR2-like protein 2 , SIR2-like protein 2 , SIRT2, SIRT2, SIRT2 , SIRT2 , SIR2L, SIR2L, SIR2L , SIR2L , SIR2L2, SIR2L2, SIR2L2 , SIR2L2 , SIR2, SIR2, SIR2 , SIR2 |
Gene, Accession # | SIRT2, Gene ID: 22933, UniProt: Q8IXJ6 |
Catalog # | abx117000 |
Price | please inquire |
Order / More Info | Sirtuin 2 (SIRT2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950