Ubiquitin-Like Modifier-Activating Enzyme 3 (UBE1C) Antibody from ABBEXA LTD
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| Antigenic Specificity | Ubiquitin-Like Modifier-Activating Enzyme 3 (UBE1C) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Immunogen | KLH-conjugated synthetic peptide between 415-445 amino acids from the C-terminal region of human UBE1C. |
| Other Names | UBA3, UBE1C, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1C, Ubiquitin-activating enzyme E1C, Ubiquitin-like modifier-activating enzyme 3, UBA3, UBA3, UBA3 , UBA3 , UBE1C, UBE1C, UBE1C , UBE1C , NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 catalytic subunit , NEDD8-activating enzyme E1 catalytic subunit , NEDD8-activating enzyme E1C, NEDD8-activating enzyme E1C, NEDD8-activating enzyme E1C , NEDD8-activating enzyme E1C , Ubiquitin-activating enzyme E1C, Ubiquitin-activating enzyme E1C, Ubiquitin-activating enzyme E1C , Ubiquitin-activating enzyme E1C , Ubiquitin-like modifier-activating enzyme 3, Ubiquitin-like modifier-activating enzyme 3, Ubiquitin-like modifier-activating enzyme 3 , Ubiquitin-like modifier-activating enzyme 3 |
| Gene, Accession # | UniProt: Q8TBC4 |
| Catalog # | abx025815 |
| Price | please inquire |
| Order / More Info | Ubiquitin-Like Modifier-Activating Enzyme 3 (UBE1C) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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