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Antigenic Specificity | Aldo-Keto Reductase Family 1 Member C4 (AKR1C4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AKR1C4 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. |
Immunogen | KLH-conjugated synthetic peptide between 11-39 amino acids from the N-terminal region of human AKR1C4. |
Other Names | 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, Chlordecone reductase, CDR, Dihydrodiol dehydrogenase 4, DD-4, DD4, HAKRA, AKR1C4, CHDR, 3-alpha-HSD, C11, aldo-keto reductase family 1, member C4, HGNC:387, MGC22581, 3-alpha hydroxysteroid dehydrogenase, type I, 3 alpha-hydroxysteroid dehydrogenase/dihydrodiol dehydrogenase 4, 3-alpha-hydroxysteroid dehydroge, Aldo-keto reductase family 1 member C4, aldo-keto reductase family 1 member C4 (chlordecone reductase, 3-alpha hydroxysteroid dehydrogenase, type I, dihydrodiol dehydrogenase 4), 3-alpha-HSD1, 3-alpha-HSD1, 3-alpha-HSD1 , 3-alpha-HSD1 , 3-alpha-hydroxysteroid dehydrogenase type I, 3-alpha-hydroxysteroid dehydrogenase type I, 3-alpha-hydroxysteroid dehydrogenase type I , 3-alpha-hydroxysteroid dehydrogenase type I , Chlordecone reductase, Chlordecone reductase, Chlordecone reductase , Chlordecone reductase , CDR, CDR, CDR , CDR , Dihydrodiol dehydrogenase 4, Dihydrodiol dehydrogenase 4, Dihydrodiol dehydrogenase 4 , |
Gene, Accession # | AKR1C4, UniProt: P17516 |
Catalog # | abx028769 |
Price | please inquire |
Order / More Info | Aldo-Keto Reductase Family 1 Member C4 (AKR1C4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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