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Antigenic Specificity | DNA Methyltransferase 3 Beta (DNMT3B) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DNMT3B antibody is a Rabbit polyclonal antibody against DNMT3B. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]. |
Immunogen | A synthetic peptide of human DNMT3B. |
Other Names | DNA (cytosine-5)-methyltransferase 3B, DNA methyltransferase HsaIIIB, DNA MTase HsaIIIB, M.HsaIIIB, DNMT3B, DNA (cytosine-5) methyltransferase 3B, ICF, ICF1, DNA (cytosine-5)-methyltransferase 3B, DNA (cytosine-5)-methyltransferase 3B, DNA (cytosine-5)-methyltransferase 3B , DNA (cytosine-5)-methyltransferase 3B , DNA methyltransferase HsaIIIB, DNA methyltransferase HsaIIIB, DNA methyltransferase HsaIIIB , DNA methyltransferase HsaIIIB , DNA MTase HsaIIIB, DNA MTase HsaIIIB, DNA MTase HsaIIIB , DNA MTase HsaIIIB , M.HsaIIIB, M.HsaIIIB, M.HsaIIIB , M.HsaIIIB , DNMT3B, DNMT3B, DNMT3B , DNMT3B , DNA (cytosine-5) methyltransferase 3B, DNA (cytosine-5) methyltransferase 3B, DNA (cytosine-5) methyltransferase 3B , DNA (cytosine-5) methyltransferase 3B , ICF, ICF, ICF , ICF , ICF1, ICF1, ICF1 , ICF1 |
Gene, Accession # | DNMT3B, Gene ID: 1789, UniProt: Q9UBC3 |
Catalog # | abx002130 |
Price | please inquire |
Order / More Info | DNA Methyltransferase 3 Beta (DNMT3B) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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