Edit |   |
---|---|
Antigenic Specificity | Myeloid Cell Nuclear Differentiation Antigen (MNDA) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2, 200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. |
Immunogen | KLH-conjugated synthetic peptide between 26-53 amino acids from the N-terminal region of human MNDA. |
Other Names | MNDA, myeloid cell nuclear differentiation antigen, PYHIN3, MNDA, MNDA, MNDA , MNDA , myeloid cell nuclear differentiation antigen, myeloid cell nuclear differentiation antigen, myeloid cell nuclear differentiation antigen , myeloid cell nuclear differentiation antigen , PYHIN3, PYHIN3, PYHIN3 , PYHIN3 |
Gene, Accession # | MNDA, UniProt: P41218 |
Catalog # | abx026169 |
Price | please inquire |
Order / More Info | Myeloid Cell Nuclear Differentiation Antigen (MNDA) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950