Myeloid Cell Nuclear Differentiation Antigen (MNDA) Antibody from ABBEXA LTD

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Antigenic SpecificityMyeloid Cell Nuclear Differentiation Antigen (MNDA)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC, FCM
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionThe myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2, 200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.
ImmunogenKLH-conjugated synthetic peptide between 26-53 amino acids from the N-terminal region of human MNDA.
Other NamesMNDA, myeloid cell nuclear differentiation antigen, PYHIN3, MNDA, MNDA, MNDA , MNDA , myeloid cell nuclear differentiation antigen, myeloid cell nuclear differentiation antigen, myeloid cell nuclear differentiation antigen , myeloid cell nuclear differentiation antigen , PYHIN3, PYHIN3, PYHIN3 , PYHIN3
Gene, Accession #MNDA, UniProt: P41218
Catalog #abx026169
Priceplease inquire
Order / More InfoMyeloid Cell Nuclear Differentiation Antigen (MNDA) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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