TNF Receptor Associated Factor 2 (TRAF2) Antibody from ABBEXA LTD
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| Antigenic Specificity | TNF Receptor Associated Factor 2 (TRAF2) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TRAF2 antibody is a Rabbit polyclonal antibody against TRAF2. The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined. |
| Immunogen | Recombinant protein of human TRAF2. |
| Other Names | E3 ubiquitin-protein ligase TRAF2, MGC:45012, TNF receptor associated factor 2, TNF receptor-associated factor 2, TRAF 2, TRAF2, TRAP 3, TRAP, TRAP3, Tumor necrosis factor type 2 receptor associated protein 3, Tumor necrosis factor type 2 receptor-associated protein 3, OTTHUMP00000064745, E3 ubiquitin-protein ligase TRAF2, E3 ubiquitin-protein ligase TRAF2, E3 ubiquitin-protein ligase TRAF2 , E3 ubiquitin-protein ligase TRAF2 , MGC:45012, MGC:45012, MGC:45012 , MGC:45012 , TNF receptor associated factor 2, TNF receptor associated factor 2, TNF receptor associated factor 2 , TNF receptor associated factor 2 , TNF receptor-associated factor 2, TNF receptor-associated factor 2, TNF receptor-associated factor 2 , TNF receptor-associated factor 2 , TRAF 2, TRAF 2, TRAF 2 , TRAF 2 , TRAF2, TRAF2, TRAF2 , TRAF2 , TRAP 3, TRAP 3, TRAP 3 , TRAP 3 , TRAP, TRAP, TRAP , TRAP , TRAP3, TRAP3, TRAP3 , TRAP3 , Tumor necrosis factor type 2 receptor associated protein 3, Tumor necrosis factor |
| Gene, Accession # | TRAF2, Gene ID: 7186, UniProt: Q12933 |
| Catalog # | abx000916 |
| Price | please inquire |
| Order / More Info | TNF Receptor Associated Factor 2 (TRAF2) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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