Cadherin-1 / E-Cadherin (CDH1) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Cadherin-1 / E-Cadherin (CDH1) antibody, protein, ELISA kits.
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| Antigenic Specificity | Cadherin-1 / E-Cadherin (CDH1) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse, monkey |
| Isotype | IgG1 |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | E-Cadherin is a 120 kDa transmembrane glycoprotein that is localized in the adherens junctions of epithelial cells.There, it interacts with the cytoskeleton through the associated cytoplasmic catenin proteins.In addition to being a calcium-dependent adhesion molecule, E-Cadherin is also a critical regulator of epithelial junction formation.Its association with catenins is necessary for cell-cell adhesion.These E-cadherin/catenin complexes associate with corical actin bundles at both the zonula adherens and the lateral adhesion plaques.Tyrosine phosphorylation can disrupt these complexes, leading to changes in cell adhesion properties.E-Cadherin expression is often down-regulated in highly invasive, poorly differentiated carcinomas.Increased expression of E-Cadherin in these cells reduces invasiveness.Thus, loss of expression or function of E-Cadherin appears to be an important step in tumorigenic progression.Tissue specificity: Non-neural epithelial tissues. |
| Immunogen | Purified recombinant fragment of human CDH1 expressed in E. coli. |
| Other Names | CADH1, cadherin 1, type 1, E-cadherin (epithelial) (ECAD), cadherin-1, CAM 120/80, E-cadherin, epithelial-cadherin, uvomorulin, CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO, E-Cad/CTF3, Epithelial cadherin, E-Cad/CTF1, E-Cad/CTF2, Um, E-cad, L-CAM, AA960649, E-Cadherin,, CADH1, CADH1, CADH1 , CADH1 , cadherin 1, cadherin 1, cadherin 1 , cadherin 1 , type 1, type 1, type 1 , type 1 , E-cadherin (epithelial) (ECAD), E-cadherin (epithelial) (ECAD), E-cadherin (epithelial) (ECAD) , E-cadherin (epithelial) (ECAD) , cadherin-1, cadherin-1, cadherin-1 , cadherin-1 , CAM 120/80, CAM 120/80, CAM 120/80 , CAM 120/80 , E-cadherin, E-cadherin, E-cadherin , E-cadherin , epithelial-cadherin, epithelial-cadherin, epithelial-cadherin , epithelial-cadherin , uvomorulin, uvomorulin, uvomorulin , uvomorulin , CDH1, CDH1, CDH1 , CDH1 , Arc-1, Arc-1, Arc-1 , Arc-1 , CD324, CD324, CD324 , CD324 , CDHE, CDHE, CDHE , CDHE , ECAD, ECAD, ECAD , ECAD , LCAM, LCAM, LCAM , LCAM , UVO, UVO, UVO , UVO , |
| Gene, Accession # | Gene ID: 999 |
| Catalog # | abx015807 |
| Price | please inquire |
| Order / More Info | Cadherin-1 / E-Cadherin (CDH1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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