Ubiquitin-Like Protein ISG15 (ISG15) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Ubiquitin-Like Protein ISG15 (ISG15) antibody, protein, ELISA kits.
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| Antigenic Specificity | Ubiquitin-Like Protein ISG15 (ISG15) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ISG15 is secreted from monocytes in response to type I interferons and causes natural killer (NK) cell proliferation and an augmentation of non-MCH (major histocompatibility complex) restricted cytotoxicity. Synthesis is stimulated by IFN-alpha or IFN-beta or IFN-omega, but not IFN-gamma. ISG15 expression is also induced by overexpression of interferon regulatory factors that participate in transcriptional regulation of IFN genes, and by influenza B virus. ISG15 is secreted also by cell lines of monocyte, T-lymphocyte, B-lymphocyte, human fibroblasts, and epithelial origins. The induction of terminal differentiation in human melanoma cells is associated with alterations in ISG15 expression. Enhancement of NK cell proliferation, augmentation of non-major histocompatibility complex-restricted cytotoxicity, and induction of IFN-gamma from T cells identify ISG15 as a member of the cytokine cascade and suggest that it may be responsible for amplifying and directing some of the immunomodulatory effects of IFN-alpha or IFN-beta. ISG15 has has also been shown to function intracellularly as a ubiquitin homolog. |
| Immunogen | KLH-conjugated synthetic peptide between 31-61 amino acids from the N-terminal region of human ISG15. |
| Other Names | G1P2, IP17, UCRP, IFI15, hUCRP, ISG15, Interferon-induced 15 kDa protein Interferon-induced 17 kDa protein IP17 Ubiquitin cross-reactive protein hUCRP, Ubiquitin-like protein ISG15, Interferon-induced 15 kDa protein, Interferon-induced 17 kDa protein, Ubiquitin cross-reactive protein, G1P2, G1P2, G1P2 , G1P2 , IP17, IP17, IP17 , IP17 , UCRP, UCRP, UCRP , UCRP , IFI15, IFI15, IFI15 , IFI15 , hUCRP, hUCRP, hUCRP , hUCRP , ISG15, ISG15, ISG15 , ISG15 , Interferon-induced 15 kDa protein Interferon-induced 17 kDa protein IP17 Ubiquitin cross-reactive protein hUCRP, Interferon-induced 15 kDa protein Interferon-induced 17 kDa protein IP17 Ubiquitin cross-reactive protein hUCRP, Interferon-induced 15 kDa protein Interferon-induced 17 kDa protein IP17 Ubiquitin cross-reactive protein hUCRP , Interferon-induced 15 kDa protein Interferon-induced 17 kDa protein IP17 Ubiquitin cross-reactive protein hUCRP , Ubiquitin-like protein ISG15, Ubiquitin-like protein ISG15, Ubiquitin-like protein I |
| Gene, Accession # | NCBI: NP_005092.1, UniProt: P05161 |
| Catalog # | abx026299 |
| Price | please inquire |
| Order / More Info | Ubiquitin-Like Protein ISG15 (ISG15) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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